GI disturbances, nephrotic syndrome, epigastric pain, nausea, vomiting, diarrhoea, hepatitis, rash, pruritus, wheezing, bronchospasm, prolonged bleeding time. Potentially Fatal: Bleeding or perforation through peptic ulcer, rarely blood dyscrasia or anaphylaxis, acute renal failure.

Potentiates potassium-sparing diuretics. Reduced serum levels of salicylates. Potentially Fatal: Increased levels of lithium, digoxin and methotrexate.

Hypersensitivity, active peptic ulcer or GI bleeding, history of allergic responses to aspirin or other NSAIDs, acute porphyria.

Diclofenac is a NSAID (NSAID). Paracetamol is an analgesic and antipyretic. When used together, the actions of paracetamol set in earlier and provides pain relief before the effects of diclofenac Na set in.

Analgesic nephropathy, renal or hepatic impairment, hypertension, cardiac failure, bronchospasm, patients taking diuretics and elderly, lactation.