Cefdiel Syrup

Uses of Cefdiel Syrup

Cefdinir is a cephalosporin antibiotic. Cefdinir uses include treatment of various bacterial infections, for example, bronchitis, ear infection, sinusitis,pneumonia pharyngitis, tonsillitis, and skin infections.

Side Effects of Cefdiel Syrup

Headache, dizziness, fever; nausea, vomiting, diarrhoea, abdominal pain; rash; leukopaenia, thrombocytopaenia, haemolytic anaemia. Potentially Fatal: Anaphylaxis; renal and hepatic failure.

Drug Interactions

Concomitant admin with antacids and Fe reduce the rate and extent of absorption. Probenecid reduces renal elimination. Antacids reduce rate and extent of absorption.

Contraindications

Hypersensitivity.

Mechanism of Action

Cefdinir binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Absorption: Absorbed from the GIT (oral); peak plasma concentrations after 2-4 hrs. Distribution: Widely into body tissues. Protein-binding: 60-70% Metabolism: Minimal metabolism. Excretion: Via the urine; 1.7 hrs (elimination half-life). Removed by dialysis.

Special Precautions

Penicillin-sensitive patients; superinfection; seizure; pseudomembranous colitis; pregnancy, lactation; renal or hepatic insufficiency.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

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