Cinzan-25mg DT

Side Effects of Cinzan-25mg DT

Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

Drug Interactions

CNS depressant effect enhanced with alcohol. Action potentiated by domperidone.

Contraindications

Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Mechanism of Action

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity. Absorption: Absorbed from the GIT (oral); peak plasma concentrations after 2-4 hrs. Excretion: Via faeces (as unchanged drug), via urine (as metabolites); 3-6 hrs (elimination half-life).

Special Precautions

Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.