Gramoneg TN Tablet 10S

Side Effects of Gramoneg TN Tablet 10S

Nausea, vomiting, heartburn, metallic taste, headache, dizziness, depression, insomnia, rash, dry mouth, fever, arthralgia. Rarely eosinophilia, bone marrow depression. Potentially Fatal: Rarely hypersensitivity reactions, facial and laryngeal oedema, hypotension, bronchospasm.

Drug Interactions

Antacids reduce absorption of norfloxacin from gut. Probenecid reduces urinary excretion of norfloxacin. Potentially Fatal: Increased levels of theophylline and ciclosporin, warfarin effects potentiated, disulfiram-like reactions with alcohol.

Contraindications

Hypersensitivity, neurological disorders including convulsions, blood dyscrasias, children. Pregnancy and lactation.

Mechanism of Action

Tinidazole is active against protozoa and anaerobic bacterial infections against which norfloxacin is inactive. The combination of norfloxacin and tinidazole has an extended range of antimicrobial spectrum and is effective in mixed gut infections, diarrhoeas and dysentery.

Special Precautions

Moderate renal impairment, history of or susceptibility to seizures, alcohol intake. Ensure adequate hydration and urine output.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

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