Lezo-AM Cap

Side Effects of Lezo-AM Cap

Fatigue, somnolence, dry mouth, nasopharyngitis, pyrexia, cough, epistaxis.

Drug Interactions

Additive sedation with alcohol and other CNS depressants.

Contraindications

Lactation. End-stage renal disease (CrCl <10 ml/min) or haemodialysis patients. Child 6-11 yr with renal impairment.

Mechanism of Action

Levocetirizine, an active isomer of cetirizine, selectively inhibits histamine H1-receptors. Absorption: Rapidly and extensively absorbed from the GI tract (oral); peak plasma concentration in 0.9 hr. Distribution: Protein-binding: 91-92%. Metabolism: Via aromatic oxidation, N- and O-dealkylation and taurine conjugation. Excretion: Via urine (85.4%), via faeces (12.9%), as metabolites and unchanged drug; 8 hr (plasma half-life).

Special Precautions

Renal impairment. May impair ability to drive or operate machinery

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.