Pacitane 2mg Tab 25s

Uses of Pacitane 2mg Tab 25s

Trihexyphenidyl is used in the treatment of Parkinson's disease .

Side Effects of Pacitane 2mg Tab 25s

Dry mouth, blurring of vision, constipation, urinary retention, glaucoma, confusion, drowsiness, restlessness, hallucinations. Potentially Fatal: Arrhythmias, AV dissociation, multiple ventricular ectopics.

Drug Interactions

Delayed absorption of other oral drugs. Potentially Fatal: Additive anticholinergic activity with tricyclic antidepressants, antiparkinsonian drugs, antihistaminics, phenothiazine and quinidine.

Contraindications

Patients with closed-angle glaucoma, chronic pulmonary disease, sick sinus syndrome, thyrotoxicosis, cardiac failure with tachycardia.

Mechanism of Action

Trihexyphenidyl is a tertiary amine antimuscarinic, which competitively inhibits the effects of acetylcholine at the muscarinic receptors of autonomic effector sites innervated by parasympathetic nerves. It also brings about direct and indirect antispasmodic action on smooth muscle. Onset: 1 hr. Absorption: Trihexyphenidyl is absorbed well from the GI tract after oral admin with effects visible after 1 hr. Excretion: Mainly in the urine.

Special Precautions

Glaucoma, obstructive disease of GI or genitourinary tracts. In elderly males with possible prostatic hypertrophy. Liver and renal disorders. Pregnancy and lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.