Romilast 5mg Tab 15s

Uses of Romilast 5mg Tab 15s

Montelukast is used in following conditions to ease breathing problems:
1. To prevent asthma attacks due to allergies
2. To prevent shortness of breath and wheezing during asthma attack.
3. To treat sneezing and runny nose due to allergies
4. Also used to prevent bronchospasm during exercise or long running.

Side Effects of Romilast 5mg Tab 15s

Common side effects of montelukast include
1. Dizziness, fatigue,drowsiness, fever
2. Abdominal pain, dyspepsia,gastroenteritis,pancreatitis,cholestasis, diarrhoea,
3. Cough, nasal congestion
4. Aggression and agitation
5. Angioedema, arthralgia, restlessness, palpitation
6. Bleeding tendency, bruising
7. Dream abnormalities, insomnia (lack of sleep)
8. Hypersensitivity, hypoaesthesia, , irritability, muscle cramps, myalgia
9. Nausea & vomiting
10. Rashes and urticaria

Drug Interactions

Metabolism may be increased with rifampicin, phenobarbital, phenytoin. Peripheral oedema may occur with prednisone.

Contraindications

NA

Mechanism of Action

Montelukast is a selective leukotriene receptor antagonist that blocks the effects of cysteinyl leukotrienes in the airways. Absorption: Rapidly absorbed from the GI tract (oral). Peak plasma concentrations in 2-4 hr. Mean oral bioavailability: 64%. Distribution: Protein-binding: >99%. Metabolism: Extensively hepatic by CYP3A4, CYP2A6 and CYP2C9 isoenzymes. Excretion: Principally via faeces; elimination half-life prolonged in mild to moderate hepatic impairment.

Special Precautions

Not indicated for the relief of acute bronchospasm. Not to be used as monotherapy for the prevention of exercise-induced bronchospasm.
Patients in whom asthma is precipitated by aspirin or other NSAIDs should continue to avoid aspirin and NSAIDs. Do not abruptly substitute for oral or inhaled corticosteroids. Be alert for any signs of Churg-Strauss syndrome.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.