Tritofen Syrup

Side Effects of Tritofen Syrup

Sedation, drowsiness, dizziness, dry mouth, weight gain, increased appetite, CNS stimulation. Rarely, cystitis. Conjunctival injection, headaches and rhinitis (ophthalmic).

Drug Interactions

Reduced platelet count with oral antidiabetics. Potentially Fatal: May potentiate CNS effects of sedatives, hypnotics, antihistamines and alcohol.

Contraindications

Acute asthma attack.

Mechanism of Action

Ketotifen selectively and noncompetitively inhibits the release of mediators from cells involved in hypersensitivity reactions. It is also a mast cell stabiliser. Onset: Within min (ophthalmic). Absorption: Absorbed completely for the GIT (oral); bioavailability: 50%; peak plasma concentrations after 2-4 hr. Distribution: Protein-binding: 75%. Metabolism: Hepatic first-pass metabolism. Excretion: Via urine (as inactive metabolites and traces of unchanged drug); 21 hr (elimination half-life).

Special Precautions

May impair tasks requring mental alertness e.g. driving or operating machinery. History of epilepsy. Pregnancy and lactation. Children <3 yr.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

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