Torasemide is a potent loop diuretic (medicines which increase urine output) and is used to treat conditions like edema (retention of fluid in the body) and hypertension.

Electrolyte disturbances e.g. hypokalaemia, dehydration, dry mouth, headache, dizziness, hypotension, weakness, drowsiness, confusional states, loss of appetite, cramps, increased serum uric acid, glucose, lipids, urea and creatinine, increase in LFT, metabolic alkalosis, tinnitus and hearing loss.

Increased risk of severe hypokalaemia with amphotercin B, corticosteroids, carbenoxolone, hypokalaemia-causing medications. Increased risk of lithium toxicity. Increased potential for ototoxicity and nephrotoxicity with nephrotoxic or ototoxic medications e.g. aminoglycosides. High dose salicylates may increase the risk of salicylate toxicity. Increased risk of toxicity with digoxin. Reduced diuretic effect with NSAIDs. Increased risk of hypotension with antihypertensives.

Hypersensitivity to sulfonylureas, renal failure with anuria, hepatic coma and pre-coma, hypotension, cardiac arrhythmias. Pregnancy and lactation.

It acts by inhibiting the Na+/K+/2Cl- co-transporter in the kidney's loop of Henle, which reduces the reabsorption of sodium and chloride ions. This mechanism promotes the excretion of water and electrolytes, aiding in the management of fluid retention associated with heart failure, liver cirrhosis, and kidney disease.

Risk of hyperuricaemia, gout and DM. Correct electrolyte distubances and disorders of micturition before treatment. Monitor electrolyte balance, glucose, uric acid, creatinine and lipids regularly. May impair ability to drive or operate machinery.

Follow the advice of your doctor before consuming/applying this medicine. For more clarification consult your pharmacist and follow the instructions inside the Meltor 40 mg Tablet pack . The dose and timing of intake/application should be as per your prescription.

Each medicine has different storage requirement pertaining to their physical and chemical properties. Follow the storage instructions of Meltor 40 mg Tablet Tablet as provided on the medicine label. It is advisable to strictly follow Meltor 40 mg Tablet storage instructions to preserve its medicinal value and prevent any decay in its properties or medical potency.

Alcohol can interact with many drugs, and the effects of these interactions can vary. Therefore, it is important to tell your doctor about your alcohol use before taking any medication.

Some drugs can pass into breast milk and be ingested by the baby. It is therefore important to inform your doctor if you are breastfeeding before starting Meltor 40 mg Tablet or any other medicine.

Here is an explanation of why this is important:

1. The amount of drug that passes into breast milk can vary depending on the drug and the dose. Some drugs are excreted in very small amounts, while others can be passed on in higher concentrations.
2. The effects of the drug on the baby can also vary. Some drugs are safe for breastfeeding babies, while others can cause side effects.
3. It is important to talk to your doctor about the risks and benefits of taking any medication while breastfeeding. Your doctor can help you decide if the medication is safe for you and your baby.

Please refer to product insert or consult with your doctor.

The liver is a vital organ that helps to metabolize (break down) drugs. If the liver is not functioning properly, it may not be able to metabolize drugs as effectively. This can lead to a number of problems, including:

1. The drug may not work as well as it should.
2. The drug may build up in the body, leading to toxicity.
3. The drug may interact with other medications, causing unexpected side effects.

If you have any liver problems, it is important to tell your doctor before starting any new medication. Your doctor can help you to choose a medication that is safe for you and that will be metabolized effectively by your liver.

Many drugs are removed from the body through the kidneys. This means that if your kidneys are not working properly, the drugs may build up in your body and cause problems. Additionally, some drugs can actually damage the kidneys, so it is important to be aware of this risk if you have kidney problems.

For these reasons, it is advisable to have your kidney function regularly monitored while you are taking any medication. This will help to ensure that the drugs are not causing any harm to your kidneys. If you have any kidney problems, be sure to tell your doctor so that they can adjust your medication dosage or recommend other medications that are less likely to affect your kidneys.

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