Acamptas 333mg Tablet 6s

Uses of Acamptas 333mg Tablet 6s

Acamprosate affects chemicals in the brain that may become unbalanced in a person who is addicted to alcohol. Acamprosate works by restoring this chemical balance in the brain in an alcohol-dependent person who has recently quit drinking. Acamprosate is used together with behavior modification and counseling support to help a person who has recently quit drinking alcohol continue to choose not to drink. Acamprosate is not likely to be helpful if you have not already quit drinking or undergone detoxification. It may not help you if you are also addicted to other substances besides alcohol.

Side Effects of Acamptas 333mg Tablet 6s

GI disturbances (diarrhoea, nausea, vomiting, abdominal pain, asthenia), dermatological (pruritus, rash).

Drug Interactions

Coadmin with naltrexone may increase the plasma concentration of acamprosate.

Contraindications

CrCl <30 ml/min.

Mechanism of Action

Affects the balance of GABA and glutamate neurotransmitters by decreasing glutamergic transmission and modulation of neuronal hyperexcitability. Absorption: Absolute bioavailability is 11%. Steady-state plasma concentrations are reached within 5 days of dosing. Distribution: Volume of distribution after IV admin: 72-109 L. Excretion: Excreted as unchanged drug by the kidneys.

Special Precautions

Monitor renal function. Monitor for signs of depression/suicidal tendency. Initiate with lower doses in elderly. Caution when used in patients with suicide ideation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.