Alupent Syrup

Side Effects of Alupent Syrup

Tachycardia, nervousness, increased serum glucose, increased potassium levels, tremor, palpitation, headache, dizziness, insomnia, nausea, vomiting, bad taste, heartburn, xerostomia, trembling, muscle cramps, weakness, coughing, pharyngitis, increased diaphoresis, paradoxical bronchospasm, hypertension, chest pain, angina, drowsiness, diarrhoea, taste change.

Drug Interactions

Effects may be antagonised by β-blockers e.g. propranolol. Duration of bronchodilation may be increased with inhaled ipratropium. Increased adverse effects with MAOIs, TCAs, sympathomimetics. Potentially Fatal: Increased risk of malignant arrhythmias with halothane.

Contraindications

Cardiac arrhythmias associated with tachycardia.

Mechanism of Action

Orciprenaline is a direct acting sympathomimetic with predominantly β2-adrenoceptor stimulant activity. It has minimal effect on heart rate. Onset: Inhaler: Within 1 min. Nebuliser: 5-30 min. Oral: 15 min. Duration: Up to 6 hr (inhalation). Absorption: Absorbed from the GI tract (oral). Metabolism: Hepatic; undergoes extensive first-pass metabolism. Excretion: Via urine (mainly as metabolites).

Special Precautions

CV disease (e.g. arrhythmia, hypertension, CHF), DM, glaucoma, hyperthyroidism, hypokalaemia, seizure disorders. Pregnancy and lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.