Amplus Injection

Uses of Amplus Injection

Amoxicillin is a penicillin antibiotic that fights bacteria. Amoxicillin is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, gonorrhea, and infections of the ear, nose, throat, skin, or urinary tract.

Side Effects of Amplus Injection

GI upsets, rash, urticaria, neutropenia, neurotoxicity, agranulocytosis (rarely), increased incidence of phlebitis with IV use. Potentially Fatal: Rarely anaphylactic shock; pseudomembranous colitis.

Drug Interactions

Failure of OC may occur, loss of potency of cloxacillin in soln. reported with erythromycin, gentamicin, kanamycin, colistin, oxytetracycline, chlorpromazine, Vit.C, & polymyxin B sulphate. Products containing cloxacillin should not be added to IV lipids, blood products, protein hydrolysates or other proteinaceous fluids. Chloramphenicol & tetracycline antagonise bactericidal effect of penicillins. Probenecid prolongs serum drug concentration; Sulfonamides & aspirin inhibit serum protein binding of cloxacillin, thereby increasing serum-free drug levels. Potentially Fatal: None reported.

Contraindications

Hypersensitivity to penicillins.

Mechanism of Action

Amoxicillin is bactericidal against non β-lactamase producing gm+ve organisms and selected gm-ve pathogens. Cloxacillin is a β-lactamase resistant penicillin active against gm+ve organisms including β-lactamase (penicillinase) producing strains of Staphylococci. It is highly active against Staph aureus, Strep pyogenes, Strep viridans and Strep pneumoniae. Also effective against penicillinase producing gonococci and against N meningitidis and H influenzae.

Special Precautions

Allergy to cephalosporins, infectious mononucleosis, neonates with jaundice, H/o convulsions, lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.