Bricanyl-5mg Tab 20s

Side Effects of Bricanyl-5mg Tab 20s

Fine skeletal muscle tremor esp hands, dizziness, anxiety, flushes, sweating, nausea, vomiting, lethargy, tinnitus, tachycardia, palpitations, muscle cramps, headache, paradoxical bronchospasm. IV: Transient hyperglycemia, transient hypokaelemia. Potentially Fatal: (IV): MI, pulmonary oedema, ketoacidosis.

Drug Interactions

Antagonised effects of β-blockers. Increased risk of hypokaelemia with xanthine derivatives, corticosteriods and diuretics; increased risk of arrhythmias with inhaled anaesthetics, sympathomimetics.

Contraindications

Hypersensitivity to sympathomimetics. Any condition of mother or foetus in which prolongation of pregnancy is dangerous.

Mechanism of Action

Terbutaline is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by selective action on β2 receptors. It also decreases uterine contractility. Onset: Inhalation: 5 min; Oral: 30 min. Duration: Inhalation: 3-4 hr; Oral: 8 hr. Absorption: Absorbed from the GI tract. Distribution: Some amounts cross the placenta and appear in breast milk. Half-life: 3 to 4 hr. Metabolism: 60% of absorbed dose undergoes first-pass metabolism by sulphate conjugation in the liver and gut wall. Excretion: Via the urine partly as inactive conjugates and partly as unchanged drug.

Special Precautions

Arrhythmias, hyperthyroidism, hypertension, diabetes, myocardial insufficiency, history of seizures, heart disease.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.