Lipicure TG 10mg Tablet 10s

Uses of Lipicure TG 10mg Tablet 10s

Atorvastatin and fenofibrate are also used to treat a condition called mixed dyslipidemia, which is a combination of high cholesterol and high triglycerides. These are two different types of medications that are used to lower cholesterol. Atorvastatin is a statin, which works by blocking the production of cholesterol in the liver. Fenofibrate is a fibrate, which works by increasing the breakdown of cholesterol in the body.

Atorvastatin and fenofibrate are often used together because they work in different ways to lower cholesterol. This can help to achieve a better overall cholesterol level than using either medication alone.

Side Effects of Lipicure TG 10mg Tablet 10s

The most common side effects of atorvastatin and fenofibrate are:

1. Muscle pain
2. Nausea
3. Diarrhea
4. Headache
5. Constipation
6. Upset stomach
7. Fatigue

Drug Interactions

Concurrent Administration With Colestipol May Reduce The Serum Levels Of Atorvastatin By About 25%. Concurrent Administration With Digoxin May Increase Steady-State Plasma Digoxin Levels By About 20%. Increased Risk Of Myopathy When Used With Erythromycin. Concurrent Use Of Atorvastatin With Oral Contraceptives Containing Norethindrone And Ethinyl Estradiol May Increase Plasma Levels Of Norethindrone And Ethinyl Estradiol. Monitor Prothrombin Time/INR When Used With Oral Anticoagulants. Increased Risk Of Myopathy When Used With Ciclosporin Or Azole Antifungals/Niacin. Potentially Fatal: Co-Administration With Antacids Susp Decreased Atorvastatin Levels. Plasma Levels Of Atorvastatin Decreased With Co-Administration Of Colestipol. Decrease In Antihyperlipidaemic Activity May Occur With Propranolol. Fenofibrate Increases The Clotting Time And Causes Bleeding Complications When Co-Administered With Oral Anticoagulants.

Contraindications

Hypersensitivity, Hepatic Or Severe Renal Dysfunction, Unexplained Persistent Liver Function Abnormality, Unexplained Persistent Elevations Of Serum Transaminases Exceeding 3 Times The Upper Limit Of Normal. Preexisting Gallbladder Disease. Pregnancy And Lactation.

Mechanism of Action

Atorvastatin and fenofibrate work in different ways to lower cholesterol.

1. Atorvastatin is a statin: Statins work by blocking the production of cholesterol in the liver. Cholesterol is a type of fat that is essential for the body, but too much cholesterol can build up in the blood and increase your risk of heart disease.
2. Fenofibrate is a fibrate: Fibrates work by increasing the breakdown of cholesterol in the body. They also help to increase the production of HDL cholesterol, which is known as "good" cholesterol.

Special Precautions

Uncomplicated Myalgia, Patients Who Consume Substantial Quantities Of Alcohol And Have A History Of Liver Disease. Monitor LFTs Before Starting Therapy And At 12 Wk After Starting And Periodically Thereafter. Treatment Should Be Temporarily Discontinued In Patients With Acute, Serious Condition Suggestive Of Myopathy Or Having Risk Factor Predisposing To The Development Of Renal Failure Secondary To Rhabdomyolysis. Fenofibrate May Increase Risk Of Cholelithiasis; Discontinue If Gallbladder Stones Are Found. Fenofibrate May Increased Risk Of Pancreatitis. Renal Impairment. Safety And Efficacy Have Not Been Established In Paediatrics.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.