Seizgard 200 mg Tablet 10s

Side Effects of Seizgard 200 mg Tablet 10s

Diarrhoea (dose-related), nausea, vomiting, hypokalaemia, bloating and abdominal cramps. Potentially Fatal: Dehydration and hypernatraemia on aggressive treatment.

Drug Interactions

May prevent release of mesalazine in the colon. Decreased effect with oral neomycin, antacids.

Contraindications

Galactosaemia, intestinal obstruction. Patients on low galactose diet.

Mechanism of Action

Lactulose promotes peristalsis by producing an osmotic effect in the colon with resultant distention. In hepatic encephalopathy, it reduces absorption of ammonium ions and toxic nitrogenous compounds, resulting in reduced blood ammonia concentrations. Onset: 48 hr. Absorption: Not appreciable (oral). Metabolism: Via colonic flora to lactic acid and acetic acid. Excretion: Faeces, urine (as unchanged drug).

Special Precautions

Monitor electrolyte imbalance. Lactose intolerance; diabetics.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

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