Substitutes for Zilos-25mg Tab
| Medicine | Company | Price | You Save |
|---|---|---|---|
| Giftan 25mg Tablet 10s | Systopic | ₹15.50 | — |
| Oslo K 25mg Tablet 10s | G.M.H Laboratories | ₹21.00 | — |
| Losanorm-25 Tab | Ipca Labs | ₹24.75 | — |
| Lostat-25 Tab | Blue Cross | ₹25.50 | — |
| Actilop-25mg Tab | Active HC | ₹26.00 | — |
| Losarmed-25 Tab | Mankind Pharma | ₹28.00 | — |
| Cosart 25mg Tablet 10s | Cipla | ₹28.17 | — |
| Alsartan-25 Tab | Aristo Pharma | ₹28.20 | — |
| Zaart 25 mg Tablet 10s | CIPLA | ₹28.93 | — |
| Losatrust 25 mg Tablet 10s | Centaur Labs | ₹28.94 | — |
| Repace 25mg Tab | Sun Pharma | ₹28.94 | — |
| Lara-25mg Tab | Alkem Labs | ₹28.95 | — |
| Losartas 25mg Tablet 10s | INTAS | ₹30.50 | — |
| Angizaar 25mg Tablet 10s | Micro Labs | ₹30.75 | — |
| Covance-25 Tab | Sun Pharma | ₹31.65 | — |
| Tozaar 25mg Tablet 10s | Torrent Pharma | ₹31.70 | — |
| Revas-25mg Tab 10s | Alembic Pharma | ₹34.70 | — |
| Omnitan-25 Tab | Macleods | ₹39.76 | — |
| Nusar 25mg Tab | Emcure Pharma | ₹40.96 | — |
| Losium-25 Tab | Cadila Pharma | ₹44.40 | — |
| Losar-25mg Tab | Unichem | ₹52.00 | — |
Uses of Zilos-25mg Tab
Antihypertensive. It is used in the management of high blood pressure.
Side Effects of Zilos-25mg Tab
Headache, dizziness, back pain, myalgia, respiratory tract disorders, asthenia/fatigue, first dose hypotension, rash, angioedema, neutropenia, GI disturbances, transient elevation of liver enzymes, impaired renal function, taste disturbances and hyperkalaemia.
Drug Interactions
Hypotensive effect of losartan potentiated by diuretics and other antihypertensives. Risk of hyperkalaemia increases with concomitant ACE inhibitors, ciclosporin, potassium-sparing diuretics and K supplements. Hypotensive effect may be antagonised and increased risk of renal impairment when used with NSAIDs. Potentially Fatal: Risk of lithium toxicity with losartan use.
Contraindications
Pregnancy, lactation; children with CrCl <30 ml/min/1.73m2.
Mechanism of Action
Losartan is an angiotensin II receptor antagonist. The drug and its active metabolite selectively block the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively antagonising its binding to AT1 receptors. Absorption: Readily absorbed from GI tract with peak plasma concentrations of losartan after around 1 hr and its active metabolite after 3-4 hr. Distribution: 98% plasma protein bound. Metabolism: Hepatic metabolism principally by isoenzymes CYP3A4 and 2C9. Excretion: Excreted in faeces and urine as metabolites and unchanged drug. Terminal elimination half life of 2 hr (losartan) and 6-9 hr (active metabolite).
Special Precautions
Volume-depleted patients including patients on diuretics and salt restriction; renal artery stenosis; elderly; renal or hepatic impairment. Monitor serum-potassium concentration.
How to Use
Take orally with food and water, as directed by your physician.
How to Store
Keep in a cool, dry place away from sunlight and moisture.
Safety Concerns
- Alcohol: Avoid during treatment.
- Breastfeeding: Not recommended.
- Pregnancy: Contraindicated.
- Liver/Kidney: Use with caution.
Content Disclaimer
This content is for educational purposes only. Please consult your doctor before use.
More brands by FDC
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|---|---|---|
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Written by: SastiMedic Medical Team
Reviewed by: Registered Pharmacist