Albucid 20% Eye Drop

Side Effects of Albucid 20% Eye Drop

Hypersensitivity skin reaction. Ophthalmic: Burning, stinging, conjunctivitis, corneal ulcers, irritation, conjunctival hyperaemia. Systemic absorption from inflamed conjunctiva. Potentially Fatal: Stevens-Johnson syndrome.

Drug Interactions

Action antagonised by PABA and procaine group of local anaesthetics. PABA present in purulent eye exudates can competitively inhibit the action of sulphacetamide.

Contraindications

Hypersensitivity; infants <2 mth.

Mechanism of Action

Sulfacetamide has bacteriostatic effect on a wide range of gram-positive and gram-negative organisms. It interferes with nucleic acid synthesis thus blocking conversion of PABA to the coenzyme dihydrofolic acid. Absorption: Penetrates into ocular tissues and fluids (ophthalmic). Excretion: Urine (as unchanged drug); 7-13 hr (elimination half-life).

Special Precautions

Elderly. History of allergy or asthma; G6PD deficiency; renal and hepatic impairment. Prolonged therapy requires CBC and urinalysis with microscopic examination. Maintain adequate fluid intake. Pregnancy, lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

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