Betagan Eye Drop

Side Effects of Betagan Eye Drop

Ocular stinging, burning, blepharoconjunctivitis, decreased heart rate, decreased BP, iridocyclitis, headache, transient ataxia, dizziness, lethargy, decreased corneal sensitivity, tearing, visual disturbances, urticaria and pruritus.

Drug Interactions

Mydriasis may occur when used with epinephrine. Additive effects with catecholamine-depleting drugs e.g. reserpine. Possible AV conduction disturbances, LVF and hypotension with IV calcium antagonists. Additive prolongation of AV conduction time with digitalis and calcium antagonists. Additive hypotensive effects with phenothiazine-related agents. Additive effect with systemic β-blockers.

Contraindications

Bronchial asthma, severe COPD; sinus bradycardia; 2nd and 3rd degree heart block; overt cardiac failure; cardiogenic shock.

Mechanism of Action

Levobunolol, a nonselective β-adrenergic blocking agent, decreases IOP by reducing aqueous humour production. Onset: Within 1 hr (ophthalmic). Duration: Up to 24 hr (ophthalmic). Absorption: Rapidly and almost completely absorbed from the GI trac t (oral). Metabolism: Extensively hepatic. Excretion: Via urine as metabolites and unchanged drug.

Special Precautions

Patients at risk of developing hypoglycaemia. DM. Thyrotoxicosis. Known diminished pulmonary function. Cerebrovascular insufficiency. Do not drive or operate machinery until vision is clear. Pregnancy and lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.