Bufex-C Tab

Side Effects of Bufex-C Tab

Drowsiness, dizziness, lightheadedness, headache, excitement, restlessness, GI disturbances, irritability, sensitivity reactions (skin rash). Jaundice, liver damage reported. Orange or reddish-purple urine. Potentially Fatal: Anaphylactoid reactions, angioedema, fatal hepatocellular toxicity.

Drug Interactions

Potentially Fatal: Additive effect when used with other CNS depressants or alcohol.

Contraindications

Hypersensitivity. Liver disease. Porphyria. Lactation.

Mechanism of Action

Chlorzoxazone acts at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic areas involved in producing and maintaining skeletal muscle spasm of varied etiology, thus relieving painful musculoskeletal conditions. It also has sedative property. Onset: 1 hr. Duration: 3-4 hr. Absorption: Completely absorbed from the GI tract (oral); peak plasma concentrations after 1-2 hr. Metabolism: Hepatic; yielding 6-hydroxychlorzoxazone. Excretion: Via urine (mainly as glucuronide); 1 hr (elimination half-life).

Special Precautions

Pregnancy, known allergies. Tasks requiring mental alertness may be impaired. Monitor liver function.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.