Cizorest OD 400 mg Tablet 10s

Uses of Cizorest OD 400 mg Tablet 10s

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Side Effects of Cizorest OD 400 mg Tablet 10s

Weight gain, dizziness, postural hypotension, extrapyramidal symptoms, neuroleptic malignant syndrome. GI disorders and dry mouth. CNS effects. Hyperprolactinaemia (with galactorrhoea, amenorrhoea, gynecomastia, breast pain, sexual dysfunction).

Drug Interactions

Guanethidine and other adrenergic neuron blockers, antiarrhythmics, antihistamines, antimalarials and cisapride, diuretics, general anaesthetics, hypnotics, anxiolytics and opioids. Metoclopramide may increase the risk of antipsychotic-induced extrapyramidal effects. Avoid alcohol.

Contraindications

Pregnancy and lactation, pheochromocytoma, prolactin-dependent tumors. Children <15 yr.

Mechanism of Action

Amisulpride is a substituted benzamide atypical antipsychotic with general properties similar to those of sulpiride and is reported to have a high affinity for dopamine D2 and D3 receptors. Absorption: Bioavailability: about 48%. Distribution: Protein binding: about 16%. Metabolism: Limited metabolism. Excretion: Terminal half-life: 12 hr. Mainly excreted unchanged in urine.

Special Precautions

Renal impairment, Parkinson's disease, CV disease, history of epilepsy, elderly. May affect performance of skilled tasks. withdraw gradually and closely monitored to avoid relapse. Elderly.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.