Ontramab 150mg Injection
MRP: ₹10,500.00
Packaging
INJECTION
Composition
Trastuzumab 150mg
Company
Celon Labs
Substitutes for Ontramab 150mg Injection
| Medicine | Company | Price | You Save |
|---|---|---|---|
| Eleftha 150mg Injection | Intas | ₹6,225.00 | Save ₹4,275.00 |
| Hersima 150mg Injection | Alkem Labs | ₹19,132.00 | — |
| Hertraz 150mg Injection | Mylan Pharmaceuticals | ₹19,500.00 | — |
| Hermab 150mg Injection | RPG Life Sciences | ₹19,500.00 | — |
| Hervycta 150mg Injection | Dr. Reddy | ₹20,300.00 | — |
| Neuzumab 150mg Injection | Lupin | ₹20,500.00 | — |
| Trumab 150mg Injection | Glenmark | ₹20,600.00 | — |
| Canmab 150mg Injection | Biocon Ltd | ₹21,430.00 | — |
| Vivitra 150mg Injection | Zydus Cadila | ₹22,400.00 | — |
| Trazumab 150mg Injection | Emcure Pharma | ₹23,210.00 | — |
| Trasturel 150mg Injection | Reliance | ₹24,200.00 | — |
Uses of Ontramab 150mg Injection
Trastuzumab is an anti cancer medicine and is used in the treatment of following types of cancer
- breast cancer,
- oesophageal cancer and
- stomach cancer.
Side Effects of Ontramab 150mg Injection
Chills, fever, headache, dizziness, back pain, arthralgia, increased cough, infection, insomnia, oedema, tachycardia, diarrhoea, paresthesia and rashes. Potentially Fatal: Severe hypersensitivity (anaphylaxis) and infusion reactions; pulmonary events e.g. acute respiratory distress syndrome; cardiotoxicity. Neutropenia (especially when given with chemotherapy).
Drug Interactions
Increased risk of severe cardiotoxicity with anthracyclines. Increased risk of leukopenia and anaemia in combination chemotherapy (e.g. paclitaxel). Paclitaxel may decrease the clearance of trastuzumab. Increased risk of bleeding with warfarin.
Contraindications
Lactation (start only 6 mth after last dose of drug). Do not admin by rapid IV or bolus inj.
Mechanism of Action
Trastuzumab, a monoclonal antibody, has action directed against a cell surface protein produced by human epidermal growth factor receptor 2 (HER2). It inhibits proliferation of tumour cells that overexpress HER2 e.g. in 1/3 of breast cancer. Distribution: Vd: 44 mL/kg; unlikely to cross intact blood brain barrier. Excretion: Half-life ranges from 5.8 to 28.5 days after admin of the recommended doses.
Special Precautions
Preexisting cardiac dysfunction and pulmonary disease (e.g. asthma, COPD), prior cardiotoxic therapy, extensive tumour involvement of lungs. Monitor cardiac function frequently and watch for signs of cardiotoxicity (ventricular dysfunction or CHF). Pregnancy, elderly.
How to Use
Take orally with food and water, as directed by your physician.
How to Store
Keep in a cool, dry place away from sunlight and moisture.
Safety Concerns
- Alcohol: Avoid during treatment.
- Breastfeeding: Not recommended.
- Pregnancy: Contraindicated.
- Liver/Kidney: Use with caution.
Content Disclaimer
This content is for educational purposes only. Please consult your doctor before use.
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|---|---|---|
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Written by: SastiMedic Medical Team
Reviewed by: Registered Pharmacist