Pubergen 5000 I.u. Injection
MRP: ₹411.30
Packaging
1 INJECTION
Composition
Chorionic Gonadotrophin 5000IU
Company
Unichem
Substitutes for Pubergen 5000 I.u. Injection
| Medicine | Company | Price | You Save |
|---|---|---|---|
| Ovunal SC 5000iu Injection | INTAS | ₹389.96 | Save ₹21.34 |
| Lupi HCG HP 5000 IU Injection | Lupin | ₹397.18 | Save ₹14.12 |
| Coriosurge HP 5000 IU Injection | Intas | ₹397.65 | Save ₹13.65 |
| Coriosurge XP 5000iu Injection | INTAS | ₹397.65 | Save ₹13.65 |
| Lupi HCG 5000 IU Injection | Lupin | ₹410.83 | Save ₹0.47 |
| Ovidac 5K Injection | Bayer (India) | ₹457.00 | — |
| Ovigyn-5000 IU Injection | Alembic Pharma | ₹467.00 | — |
| Life 5000 IU Injection | Abbott India | ₹475.00 | — |
| Intas HCG 5000 IU Injection | INTAS | ₹480.00 | — |
| Ovunal HP 5000 IU Injection | INTAS | ₹480.00 | — |
| Fertigyn HP 5000iu Injection | Sun Pharma | ₹550.00 | — |
| Fertigyn-5000 IU Inj. | Sun Pharma | ₹550.00 | — |
| Profasi-5000 IU Inj. | Serum International | ₹1,295.00 | — |
Uses of Pubergen 5000 I.u. Injection
Chorionic Gonadotrophin has actions similar to Luteinizing hormone (LH) and is used both in males and females for different purposes. In females, chorionic gonadotropin is used along with other medications like menotropins and urofollitropin to improve chances of conception.In males, LH and chorionic gonadotropin stimulate the testes to produce male hormones such as testosterone.
Side Effects of Pubergen 5000 I.u. Injection
Headache, irritability, restlessness, depression, fatigue, oedema; precocious puberty, gynaecomastia; pain at Inj site; enlargement of preexisting ovarian cysts and possible rupture; arterial thromboembolism; shock; abdominal pain. Potentially Fatal: Ovarian hyperstimulation syndrome (OHSS).
Contraindications
Hypersensitivity; precocious puberty, prostatic carcinoma or other androgenic dependent neoplasm. Pregnancy and lactation.
Mechanism of Action
Chorionic Gonadotrophin is a polypeptide hormone produced by the human placenta. It stimulates the production of gonadal steroid hormones by inducing interstitial cells (Leydig cells) of the testis to produce androgens and the corpus luteum of the ovary to produce progesterone. Absorption: Peak concentrations after 6 hrs (IM). Distribution: Mainly in the gonads. Excretion: Via the urine (10-12% of IM dose within 24 hrs). Elimination half-life: 6-11 hrs (initial phase), 23-38 hrs (terminal phase).
Special Precautions
Discontinue therapy if signs of precocious puberty are seen in patients treated for cryptorchidism. Patients with cardiac or renal disease, epilepsy, migraine or asthma.
How to Use
Take orally with food and water, as directed by your physician.
How to Store
Keep in a cool, dry place away from sunlight and moisture.
Safety Concerns
- Alcohol: Avoid during treatment.
- Breastfeeding: Not recommended.
- Pregnancy: Contraindicated.
- Liver/Kidney: Use with caution.
Content Disclaimer
This content is for educational purposes only. Please consult your doctor before use.
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Written by: SastiMedic Medical Team
Reviewed by: Registered Pharmacist