SastiMedic
Sitalent D 10mg/100mg Tablet 10s

Sitalent D 10mg/100mg Tablet 10s

MRP: ₹167.20

Packaging

TAB

Composition

Dapagliflozin 10mg + Sitagliptin 100mg

Company

Talent India

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Uses of Sitalent D 10mg/100mg Tablet 10s

  • Helps control blood sugar levels in adults with type 2 diabetes
  • Used when diet and regular exercise alone are not enough to manage diabetes
  • Helps lower both fasting and after-meal blood glucose levels
  • Can be taken along with other diabetes medicines as advised by the doctor
  • Helps the body remove excess sugar through urine
  • Supports better long-term blood sugar control and diabetes management
  • May help reduce the risk of diabetes-related complications when used regularly

Side Effects of Sitalent D 10mg/100mg Tablet 10s

  • Increased urination
  • Genital or urinary tract infections
  • Headache
  • Dizziness or feeling light-headed
  • Low blood sugar, especially when taken with insulin or sulfonylureas
  • Nausea or stomach discomfort
  • Fatigue or weakness
  • Joint pain
  • Allergic reactions such as rash or itching (rare)

Drug Interactions

  • Insulin or sulfonylureas – increased risk of low blood sugar
  • Diuretics (water pills) – increased risk of dehydration and low blood pressure
  • Other antidiabetic medicines – may require dose adjustment
  • Alcohol – may increase the risk of low blood sugar and dehydration
  • Medicines affecting kidney function – may alter drug effectiveness

Contraindications

  • Known allergy to Dapagliflozin, Sitagliptin, or any component of the medicine
  • Type 1 diabetes mellitus
  • Diabetic ketoacidosis
  • Severe kidney impairment or patients on dialysis
  • History of serious hypersensitivity reactions to DPP-4 inhibitors
  • Pregnancy and breastfeeding, unless clearly advised by a doctor

Mechanism of Action

Dapagliflozin:
Dapagliflozin works by blocking a protein called SGLT2 in the kidneys. This protein normally helps the body reabsorb sugar back into the blood. By blocking SGLT2, Dapagliflozin allows excess sugar to be removed through urine. This helps lower blood sugar levels and may also support mild weight reduction and blood pressure control.

Sitagliptin:
Sitagliptin works by increasing the levels of natural hormones called incretins. These hormones help the body release more insulin after meals and reduce the amount of sugar made by the liver. This results in better control of blood sugar levels, especially after eating.

Combined Effect:
Together, Dapagliflozin and Sitagliptin help control blood sugar in two different ways—one by removing excess sugar from the body and the other by improving insulin response. This dual action provides better and more stable blood sugar control throughout the day.

Special Precautions

  • Drink adequate fluids to avoid dehydration
  • Use with caution in patients with kidney problems
  • Monitor blood sugar regularly as advised by your doctor
  • Maintain proper personal hygiene to reduce the risk of genital infections
  • Inform your doctor if you experience repeated urinary infections
  • Use cautiously in elderly patients due to risk of dizziness and dehydration
  • Tell your doctor if you are planning surgery or fasting for long periods

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

  • Alcohol: Avoid during treatment.
  • Breastfeeding: Not recommended.
  • Pregnancy: Contraindicated.
  • Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.

More brands by Talent India

Written by: SastiMedic Medical Team

Reviewed by: Registered Pharmacist

References

  1. Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study 🔗
  2. BRIDGE-DS study: evaluating the effectiveness and safety of dapagliflozin/sitagliptin combination in type 2 diabetes mellitus patients with heart failure 🔗