Onglyza 5mg Tab 14s

Uses of Onglyza 5mg Tab 14s

Saxagliptin is used as monotherapy or in combination with other drugs for the treatment of type 2 diabetes.

Side Effects of Onglyza 5mg Tab 14s

Headache, diarrhoea, upper respiratory tract infection, nasopharyngitis. Angioedema, exfoliative dermatitis, hypoglycaemia. Potentially Fatal: Anaphylaxis and/or severe dermatologic reactions such as Stevens-Johnson syndrome.

Drug Interactions

Concurrent use may increase serum levels of digoxin. Increased risk of hypoglycaemia when used with sulphonylureas.

Contraindications

Diabetic ketoacidosis.

Mechanism of Action

Saxagliptin inhibits dipeptidyl peptidase IV (DPP-IV), resulting in prolonged active incretin levels. Incretin hormones increases insulin synthesis and release from pancreatic β-cells and reduces glucagon secretion from pancreatic α-cells. Reduced glucagon secretion leads to decreased hepatic glucose production.

Special Precautions

Discontinue treatment if there are signs of hypersensitivity. Caution when used with sulphonylureas and/or other antidiabetic medications; monitor blood glucose regularly. Renal impairment; dose adjustment may be needed. Children <18 yr. Pregnancy, lactation.

How to Use

Take orally with food and water, as directed by your physician.

How to Store

Keep in a cool, dry place away from sunlight and moisture.

Safety Concerns

• Alcohol: Avoid during treatment.
• Breastfeeding: Not recommended.
• Pregnancy: Contraindicated.
• Liver/Kidney: Use with caution.

Content Disclaimer

This content is for educational purposes only. Please consult your doctor before use.