Paraplatin 150mg Inj.
MRP: ₹2,132.00
Packaging
INJECTION
Composition
Carboplatin 150mg
Company
Bristol Myers Squibb
Substitutes for Paraplatin 150mg Inj.
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|---|---|---|---|
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| Kemocarb | Fresenius Kabi | ₹835.00 | Save ₹1,297.00 |
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| Karplat 150 mg Injection | Cadila Pharma | ₹880.82 | Save ₹1,251.18 |
| Naproplat 150mg Inj. | Miracauls | ₹900.00 | Save ₹1,232.00 |
| Carbokem-150mg Inj. | Alkem Labs | ₹944.00 | Save ₹1,188.00 |
| Cytocarb 150 mg Injection | Cipla | ₹1,048.00 | Save ₹1,084.00 |
| Unicarb 150mg Inj. | United Biotech | ₹1,485.00 | Save ₹647.00 |
Uses of Paraplatin 150mg Inj.
Carboplatin is a chemotherapy drug . It is used in the treatment of various kinds of cancer like ovarian carcinoma, lung, head and neck cancers as well as endometrial, esophageal, bladder, breast and cervical; central nervous system or germ cell tumors; osteogenic sarcoma, and as preparation for a stem cell or bone marrow transplan
Side Effects of Paraplatin 150mg Inj.
Thrombocytopenia, neutropenia, leukopenia, anaemia; nausea, vomiting, central neurotoxicity, peripheral neuropathies, ototoxicity; elevation of ALT, AST, blood urea and bilirubin levels, electrolyte disturbances; alopecia; asthenia, pain; cardiac failure, embolism and cerebrovascular accidents may occur; mucositis. Potentially Fatal: Bone marrow suppression and anaphylactic reactions.
Drug Interactions
Increased risk of ototoxicity when used with aminoglycosides.
Contraindications
Previous allergy; pregnancy, lactation; allergy to other platinum compounds; severe bone marrow depression; significant bleeding, aluminium containing needles and IV sets.
Mechanism of Action
Carboplatin is an alkylating agent which binds covalently to DNA. It modifies the cell cycle by interfering with DNA structure and function. Excretion: About 70% of a dose is excreted unchanged in the urine. Terminal half-life: 1.5-6 hr.
Special Precautions
Neonates; diminished renal function; neurotoxicity; liver function impairment.
How to Use
Take orally with food and water, as directed by your physician.
How to Store
Keep in a cool, dry place away from sunlight and moisture.
Safety Concerns
- Alcohol: Avoid during treatment.
- Breastfeeding: Not recommended.
- Pregnancy: Contraindicated.
- Liver/Kidney: Use with caution.
Content Disclaimer
This content is for educational purposes only. Please consult your doctor before use.
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Written by: SastiMedic Medical Team
Reviewed by: Registered Pharmacist
References
- Calvert et al. (1989). Carboplatin dosage: prospective evaluation of a simple formula based on renal function. – The Journal of Clinical Oncology 🔗
- Drug Label Information 🔗
- Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors 🔗